منابع مشابه
Snaring Otoferlin's Role in Deafness
Mutations in the gene encoding otoferlin are known to cause deafness, but the mechanism is unclear. In this issue, Roux et al. (2006) demonstrate that otoferlin interacts with SNARE molecules at the afferent synapses of cochlear inner hair cells to trigger exocytosis of neurotransmitter.
متن کاملSnaring the Function of α-Synuclein
It is well established that the abundant neuronal protein ␣-synuclein has a causal role in Parkinson's disease , yet the normal functions of this protein remain unclear. In this issue of Cell, Chandra et al. (2005) reveal that ␣-synuclein acts as a molecular chaperone, assisting in the folding and refolding of synaptic proteins called SNAREs. These proteins are crucial for release of neurotrans...
متن کاملEliminating Concurrency Bugs in Multithreaded Software: An Approach Based on Control of Petri Nets
We describe the Gadara project, a research effort whose goal is to eliminate certain classes of concurrency bugs in multithreaded software by controlling the execution of programs at run-time. The Gadara process involves three stages: modeling of the source code at compile time in the form of a Petri net, feedback control synthesis, and control logic implementation into the source code. The fee...
متن کاملConcurrency bugs in multithreaded software: modeling and analysis using Petri nets
In this paper, we apply discrete-event system techniques to model and analyze the execution of concurrent software. The problem of interest is deadlock avoidance in shared-memory multithreaded programs. We employ Petri nets to systematically model multithreaded programs with lock acquisition and release operations. We define a new class of Petri nets, called Gadara nets, that arises from this m...
متن کاملGood Bugs Vs . Bad Bugs
Control of micro-organisms during completion of hydraulically fractured wells is a significant component in successful development of a production system. Detrimental bacteria—“bad bugs”—such as sulfate-reducing bacteria (SRB) introduced into the reservoir during drilling or completion, can facilitate biogenic sulfide production, resulting in souring of production fluids and gas, iron sulfide f...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2004
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1647rr3